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0 0.5 1 1.5 2+ Mortality 35% Improvement Relative Risk c19rmd.com Diaz et al. Remdesivir for COVID-19 LATE TREATMENT Favors remdesivir Favors control
Diaz, 1,138 patient remdesivir late treatment study: 35% lower mortality [p=0.01] https://c19p.org/diaz
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Remdesivir and Mortality in Patients with COVID-19
Diaz et al., Clinical Infectious Diseases, doi:10.1093/cid/ciab698
19 Aug 2021    Source   PDF   Share   Tweet
Retrospective 1138 hospitalized patients in the USA, 286 treated with remdesivir, showing lower mortality with treatment.
[Gérard, Zhou] show significantly increased risk of acute kidney injury with remdesivir.
risk of death, 34.7% lower, RR 0.65, p = 0.01, treatment 33 of 286 (11.5%), control 173 of 852 (20.3%), NNT 11, adjusted per study, odds ratio converted to relative risk, multivariable Cox proportional-hazards.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Diaz et al., 8/19/2021, retrospective, USA, North America, peer-reviewed, 45 authors.
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This PaperRemdesivirAll
Late treatment
is less effective
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