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Remdesivir study #7 of 20
8/23 Late treatment study
Pasquini et al., Journal of Antimicrobial Chemotherapy, doi:10.1093/jac/dkaa321 (Peer Reviewed)
Effectiveness of remdesivir in patients with COVID-19 under mechanical ventilation in an Italian ICU
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Retrospective 51 ICU patients under mechanical ventilation, 25 treated with remdesivir, showing lower mortality with treatment.

Pasquini et al., 8/23/2020, retrospective, Italy, Europe, peer-reviewed, 9 authors.
risk of death, 16.2% lower, RR 0.84, p < 0.001, treatment 14 of 25 (56.0%), control 24 of 26 (92.3%), adjusted per study, odds ratio converted to relative risk, multivariate.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
Details of all 20 studies
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