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00.250.50.7511.251.51.752+Wang (RCT)-9%1.09 [0.54-2.18]death22/15810/78Improvement, RR [CI]TreatmentControlOlender59%0.41 [0.24-0.71]death24/312102/818Spinner (RCT)35%0.65 [0.18-2.40]death5/3844/200Pasquini16%0.84 [0.69-0.94]death14/2524/26Fried61%0.39 [0.15-0.99]death4/482,510/11,673Beigel (RCT)27%0.73 [0.52-1.03]death541521SOLIDARITY (RCT)5%0.95 [0.81-1.11]death301/2,743303/2,708Solh47%0.53 [0.39-0.70]death63/219202/424Flisiak49%0.51 [0.19-1.30]death5/12217/211Garibaldi20%0.80 [0.46-1.41]death23/30345/303Ullah-100%2.00 [0.67-5.94]death8/304/30Goldberg9%0.91 [0.70-1.17]hosp. time29113Tsuzuki9%0.91 [0.45-1.85]death9/7426/195Mahajan (RCT)-76%1.76 [0.46-6.82]death5/343/36Aghajani19%0.81 [0.46-1.46]death46945Tau​2 = 0.07; I​2 = 60.9%Late treatment24%0.76 [0.62-0.92]483/5,0683,250/18,28124% improvementAll studies24%0.76 [0.62-0.92]483/5,0683,250/18,28124% improvement15 remdesivir COVID-19 studiesc19rmd.com 6/14/21Tau​2 = 0.07; I​2 = 60.9%; Z = 2.76 (p = 0.0029)Lower RiskIncreased Risk 00.250.50.7511.251.51.752+Wang (RCT)-9%1.09 [0.54-2.18]22/15810/78Improvement, RR [CI]TreatmentControlOlender59%0.41 [0.24-0.71]24/312102/818Spinner (RCT)35%0.65 [0.18-2.40]5/3844/200Pasquini16%0.84 [0.69-0.94]14/2524/26Fried61%0.39 [0.15-0.99]4/482,510/11,673Beigel (RCT)27%0.73 [0.52-1.03]541521SOLIDARITY (RCT)5%0.95 [0.81-1.11]301/2,743303/2,708Solh47%0.53 [0.39-0.70]63/219202/424Flisiak49%0.51 [0.19-1.30]5/12217/211Garibaldi20%0.80 [0.46-1.41]23/30345/303Ullah-100%2.00 [0.67-5.94]8/304/30Tsuzuki9%0.91 [0.45-1.85]9/7426/195Mahajan (RCT)-76%1.76 [0.46-6.82]5/343/36Aghajani19%0.81 [0.46-1.46]46945Tau​2 = 0.08; I​2 = 62.3%Late treatment26%0.74 [0.59-0.93]483/5,0393,250/18,16826% improvementAll studies26%0.74 [0.59-0.93]483/5,0393,250/18,16826% improvement14 remdesivir COVID-19 mortality resultsc19rmd.com 6/14/21Tau​2 = 0.08; I​2 = 62.3%; Z = 2.63 (p = 0.0043)Lower RiskIncreased Risk 00.250.50.7511.251.51.752+Goldberg9%0.91 [0.70-1.17]hosp. time29113Improvement, RR [CI]TreatmentControlTsuzuki-27%1.27 [1.09-1.48]hosp. time74195Tau​2 = 0.05; I​2 = 79.7%Late treatment-9%1.09 [0.79-1.52]0/1030/308-9% improvementAll studies-9%1.09 [0.79-1.52]0/1030/308-9% improvement2 remdesivir COVID-19 hospitalization resultsc19rmd.com 6/14/21Tau​2 = 0.05; I​2 = 79.7%; Z = 0.53 (p = 0.3)Lower RiskIncreased Risk 00.250.50.7511.251.51.752+Wang (RCT)-9%1.09 [0.54-2.18]death22/15810/78Improvement, RR [CI]TreatmentControlOlender59%0.41 [0.24-0.71]death24/312102/818Spinner (RCT)35%0.65 [0.18-2.40]death5/3844/200Pasquini16%0.84 [0.69-0.94]death14/2524/26Fried61%0.39 [0.15-0.99]death4/482,510/11,673Beigel (RCT)27%0.73 [0.52-1.03]death541521SOLIDARITY (RCT)5%0.95 [0.81-1.11]death301/2,743303/2,708Solh47%0.53 [0.39-0.70]death63/219202/424Flisiak49%0.51 [0.19-1.30]death5/12217/211Garibaldi20%0.80 [0.46-1.41]death23/30345/303Ullah-100%2.00 [0.67-5.94]death8/304/30Tsuzuki9%0.91 [0.45-1.85]death9/7426/195Mahajan (RCT)-76%1.76 [0.46-6.82]death5/343/36Aghajani19%0.81 [0.46-1.46]death46945Tau​2 = 0.08; I​2 = 62.3%Late treatment26%0.74 [0.59-0.93]483/5,0393,250/18,16826% improvementAll studies26%0.74 [0.59-0.93]483/5,0393,250/18,16826% improvement14 remdesivir COVID-19 serious outcomesc19rmd.com 6/14/21Tau​2 = 0.08; I​2 = 62.3%; Z = 2.63 (p = 0.0043)Lower RiskIncreased Risk 00.250.50.7511.251.51.752+Wang (RCT)-9%1.09 [0.54-2.18]death22/15810/78Improvement, RR [CI]TreatmentControlWang (RCT)24%0.76 [0.29-1.95]death8/717/47Wang (RCT)-48%1.48 [0.45-4.88]death12/843/31Olender59%0.41 [0.24-0.71]death24/312102/818Spinner (RCT)35%0.65 [0.18-2.40]death5/3844/200Pasquini16%0.84 [0.69-0.94]death14/2524/26Fried61%0.39 [0.15-0.99]death4/482,510/11,673Fried-37%1.37 [0.81-2.30]ventilation11/481,956/11,673Beigel (RCT)27%0.73 [0.52-1.03]death541521SOLIDARITY (RCT)5%0.95 [0.81-1.11]death301/2,743303/2,708Solh47%0.53 [0.39-0.70]death63/219202/424Flisiak49%0.51 [0.19-1.30]death5/12217/211Flisiak58%0.42 [0.13-1.18]death4/8214/119Flisiak56%0.44 [0.21-0.86]no improv.9/12236/211Garibaldi20%0.80 [0.46-1.41]death23/30345/303Garibaldi35%0.65 [0.53-0.78]no improv.52/30380/303Ullah-100%2.00 [0.67-5.94]death8/304/30Ullah-250%3.50 [0.79-15.5]ventilation7/302/30Goldberg9%0.91 [0.70-1.17]hosp. time29113Goldberg0%1.00 [1.00-1.00]viral+29113Tsuzuki9%0.91 [0.45-1.85]death9/7426/195Tsuzuki-17%1.17 [0.37-3.69]ventilation4/749/195Tsuzuki-27%1.27 [1.09-1.48]hosp. time74195Mahajan (RCT)-76%1.76 [0.46-6.82]death5/343/36Mahajan (RCT)-112%2.12 [0.41-10.8]ventilation4/342/36Aghajani19%0.81 [0.46-1.46]death46945remdesivir COVID-19 outcomesc19rmd.com 6/14/21Lower RiskIncreased Risk
Please send us corrections, updates, or comments. Vaccines and treatments are both extremely valuable and complementary. All practical, effective, and safe means should be used. Elimination of COVID-19 is a race against viral evolution. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. Denying the efficacy of any method increases the risk of COVID-19 becoming endemic; and increases mortality, morbidity, and collateral damage. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. Treatment protocols for physicians are available from the FLCCC.
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