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0 0.5 1 1.5 2+ Mortality 36% Improvement Relative Risk c19rmd.com Zhu et al. Remdesivir for COVID-19 META ANALYSIS Favors remdesivir Favors control
Zhu, remdesivir meta analysis: 36% lower mortality [p=0.02] https://c19p.org/zhu
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Efficacy and Safety of Remdesivir for COVID-19 Treatment: An Analysis of Randomized, Double-Blind, Placebo-Controlled Trials
Zhu et al., medRxiv, doi:10.1101/2020.06.22.20136531 (Preprint) (meta analysis)
29 Jun 2020    Source   PDF   Share   Tweet
Meta analysis of Beigel and Wang RCTs showing remdesivir significantly decreased mortality (8.18% vs. 12.70%, RR 0.64 [0.44-0.92], p = 0.175).
Currently there are 36 remdesivir for COVID-19 studies, showing 19% [10‑27%] lower mortality, 24% [-5‑61%] higher ventilation, 34% [-6‑92%] higher ICU admission, and 39% [-36‑201%] higher hospitalization.
risk of death, 36.0% lower, RR 0.64, p = 0.02.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Zhu et al., 6/29/2020, preprint, 11 authors.
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This PaperRemdesivirAll
Late treatment
is less effective
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